The transcription factor c-Myb regulates CD8+ T cell stemness and

MYB insufficiency disrupts proteostasis in hematopoietic stem cells myb MYB proteins are classified into four major groups namely, 1R-MYB, 2R-MYB, 3R-MYB and 4R-MYB based on the number and position of MYB repeats mybet7 Myb genes are part of a large gene family of transcription factors found in animals and plants In humans, it includes Myb proto-oncogene like 1 and Myb-related

mybet7 Myb plays a critical role in hematopoiesis, with perturbations of its activity leading to cell deficits, cellular dysfunction, and malignancy